Monday, December 30, 2019

Biblical Allusions In Masque Of The Red Death - 720 Words

From castellated abbeys to Nights Plutonian shore, Poes works are replete with biblical innuendos. The major correspondence between his narratives and the Bible would be the many implications to the Book of Revelations in The Masque of the Red Death. Revelations tells of the collapse of civilization through four horsemen, Conquest, Famine, War, and Death. The Red Death had long devastated the country. No pestilence had ever been so fatal...(Masque 1) expresses the presence of the initial horsemen, better known as Pestilence. Conclusively, ...one by one dropped the revellers...and the life of the ebony clock went out with that of the last of the gay.(Masque 16) expounds the demise of the characters, alluding to Death. War exists in†¦show more content†¦Prince Prospero was sybaritic, as his love for luxury and pleasure blinded him from the raging pestilence outside his abbey. Fortunato had a hedonistic existence as wine connoisseur, priding himself in his knowledge of the drin k, such as when he states Luchresi cannot tell Amontillado from Sherry.(Cask 14) to debase other wine pundits in comparison to himself. William Wilson from the story of the same name was driven by lust, attempts to seduce a wedded woman during a Roman carnival. Another characterization element he uses is that many of his narrators appear to have idolatry. Egaeus is an odontophiliac, as his obsession with teeth justifies his state of shock when ...there rolled out some instruments of dental surgery, intermingled with thirty-two small, white and ivory-looking substances that were scattered to and fro about the floor.(Berenice 21). The painter in The Oval Portrait suffers from obsessive love towards his wife, indicating his adulation towards the beauty of his beloved. The narrator of The Man of the Crowd is fascinated by figures he sees outside the coffee shop window he sits behind, going so far as to stalk a man who intrigues interest. Poes stories oftentimes succumb to women portray ed as beautiful and sickly, a raw connection to the women in his life. This on its own is Poes own idolatry, and it exudes into his writing. Notwithstanding their elegance, these women create tribulations forShow MoreRelatedExamples Of Biblical Allusions In The Masque Of The Red Death758 Words   |  4 Pagesof Edgar A. Poe fills itself with biblical allusions, similar characterization, and a reoccurring idealization of females, making his narratives a look at his own life when it comes to how he writes. From castellated abbeys to Nights Plutonian shore, Poes works are replete with biblical innuendos. The major correspondence between his narratives and the Bible would be the many implications to the Book of Revelations in The Masque of the Red Death. Revelations tells of the collapseRead MoreSymbolism In The Masque Of The Red Death766 Words   |  4 PagesThe Masque of the Red Death Poe often gives memory the power to keep the dead alive. Which in the short story Poe distorts the aspect of death. By creating a memory as the trigger that reawakens death Poe reveals the theme of the story; that no matter the persons social class death comes for us all. In Edgar Allan Poe’s short story â€Å"The Masque of the Red Death† he uses literary elements such as allusion, symbolism, and allegory to convey that death is inevitable. In the short story, Poe usesRead MoreThe Pit And The Pendulum And Masque Of The Red Death1573 Words   |  7 Pagesâ€Å"The Masque of the Red Death† October 16, 2014 On my honor as a Brentwood Academy student, I have neither given nor received help on this assignment. I pledge that the work and ideas in this paper, unless otherwise cited, are mine alone. X_______________________________________________________ Purpose Statement: To write a 900 word analytical essay over Edgar Allan Poe’s short stories, â€Å"The Pit and the Pendulum† and â€Å"The Masque of the Red Death† Outline I. Introductory Paragraph A. Death isRead MoreEdgar Allan Poe s The Masque Of The Red Death1225 Words   |  5 Pagescolonial poems, to the twisted mind of Edgar Allan Poe, there is a connection. Poe’s â€Å"The Masque of the Red Death† may not seem to portray the ideas of religion but through close examination, the association will become less cloudy. Poe’s use of symbolism, narrator, word choice, helps readers unmask the idea of religion. Poe’s use of symbolism is very evident throughout the story of â€Å"The Masque of the Red Death†. Much has been made about the meaning of the rooms that fill Prince Prospero’s lavishRead MoreHow to Read Lit Like a Prof Notes3608 Words   |  15 PagesOthello—jealousy iv. Merchant of Venice—justice vs. mercy v. King Lear—aging parent, greedy children, a wise fool 7. †¦Or the Bible a. Before the mid 20th century, writers could count on people being very familiar with Biblical stories, a common touchstone a writer can tap b. Common Biblical stories with symbolic implications i. Garden of Eden: women tempting men and causing their fall, the apple as symbolic of an object of temptation, a serpent who tempts men to do evil, and a fall from innocence ii.

Saturday, December 21, 2019

Overexpression Of Mirna - 1441 Words

There are many evidences that demonstrates role played by miRNA in various cardio vascular diseases. In a study Dicer was deleted that led a phenotype in myocardial and vascular lineage. In cardiac myocytes miR-1 is the most populated. Expression levels of several miRNA like miR-10a, miR-145, miR-143 and miR-126100−102 In a study it showed that hypoxia had potential to induce the expression of miR-210 in endothelial cells. It was concluded that overexpression of miR-210 leads to increase in capillary like structure formation, when miR-210 was inhibited the tube formation and migration was decreased (15). In another study it was reported that miR-221 and miR-222 had antiangiogenic characteristics in endothelial cells. This study came up†¦show more content†¦Surprising, the target of both the miRNAs has the same target and functions in a similar way. Further study exposed that the EBV-infected cells escaped the apoptosis mechanism due to the expression of miR-155. This shows the potential of virus that controls the miRNA expression for its survival benefit (14). Micro RNA in neurodegenerative diseases- In the brain approximately 70% of the miRNA are expressed and most of it are neuron specific. MiRNA are important element for proper nervous system function. These miRNA plays a crucial role for brain function. Any disruption in the miRNA processing mechanism would cause diseases like ataxia in Purkinje cells, multiple sclerosis in oligodendrocyte cells, Parkinson’s disease in dopaminergic cells, Alzheimer’s disease in ÃŽ ±-calcium/calmodulin-dependent protein kinase type II (ÃŽ ±CaMKII)-expressing neurons (16). Recent studies on systemic miRNA profiling of peripheral blood mononuclear cells from Parkinson’s disease patients reported miR-30b, miR-26a, miR-26a are the miRNA that are with disease susceptibility (14). Mutation in the leucine-rich repeat serine/ threonine protein kinase2 cause negative regulation of the transitional repression by miRNA, which leads to Parkinson’s disease. Mutation in Drosha complex cause familiarShow MoreRelatedBreast Cancer : A Complex And Heterogeneous Disease Caused By Genetic Mutations782 Words   |  4 Pages(BRCA1 and BRCA2) [1]; loss or aberrant expression of the estrogen receptor (ER) [2]; human epidermal growth factor receptor (HER2) overexpression [3] ; lack of ER, progesterone receptor (PR), and epidermal growth factor receptor (EGFR) expression[4] ; high levels of receptor for the insulin-like growth factor receptor 1 (IGF-1R[5]; and expression of microRNA (miRNA) [6]. In addition to genetic alterations (gene amplifications, deletions, point mutations, and chromosome rearrangements), epigeneticRead MoreCdna Case Study1094 Words   |  5 Pagesand 787 known miRNAs were identified from cin1, CIN1-S, and WT strain, whereas 12 novel miRNAs were identified from all three strains. Significantly, differential expression of ex-sRNA exists among the three strains (Figure 9A) and the initial Gene Ontology (GO) and KEGG pathway analysis of miRNA targets is also consistent with the established role of Cin1 in intracellular trafficking (cin1 vs. WT, Figure 9B). Further annotation and screening of differentially expressed sRNA, miRNA target predictionRead MoreAnalysis Of Hepatocellular Carcinoma ( Hcc )1136 Words   |  5 Pagesmetastasis, and prognosis [43]. HCC is also characterized by aberrant expression of miRNAs. Respectively, upregulation and downregulation has been associated with invasion and metastasis, tumor progression, and drug resistance. Meng et al. proposed that aberrantly expressed miRNAs may regulate the expression of certain genes that control cell growth, migration, and invasion. In this study, the expression of miRNA in normal versus tumor tissue was investigated which led to the identification of overexpressedRead MoreEssay On Exosomes1006 Words   |  5 Pagesseries of sample, but the striking evidences provided by Melo and colleagues suggest that GPC1+ exosomes may serve as a potential diagnostic and screening biomarker to detect early stages of PC for possible curative surgery. In earlier studies, overexpression of surviving [393], and mislocalisation of plectin [394] in exosomes were also proposed as a biomarkers for PC. Moreover, it has also recently been found that a higher rate of patients with localized PC showed noticeable KRAS mutations in exosomalRead MoreCase Study Of DLBCA1185 Words   |  5 PagesABC-DLBCL, many investigators try to identify a miRNA or a set of miRNAs to use as a potential diagnostic biomarkers, for differentiation of ABC from GCB-DLBCL. Ago2-IP followed by sequencing is becoming the most advanced tool to determine the miRNA profile and to investigate functionally active miRNA, as it has been shown recently by Cullen et al. that the level of a miRNAs in total cellular lysate, it is not a clear indication of involvement of miRNAs in to the Ago2 complex [91]. In the presentRead MoreMir-423-3p And EBV Case Study789 Words   |  4 Pageshigher expression, compared to miR-423-5p, in total cellular profile in all four cell lines. Surprisingly in Ago2-IP-Seq, miR-423-5p found to be more expressed, compared to miR-423-3p, in all four cell lines. Also miR-423-5p were the most enriched miRNA in the Ago2-IP of all cell lines we note that both miR-423-5p and miR-423-3p were in Ago2-IP-seq and miR-423-3p was more expressed in total cellular profile, compared to miR-423-5p. In all four cell lines, this results were in accordance withRead MoreMirna Essay1141 Words   |  5 PagesThe original goal of this study was to identify miRNAs that are differentially expressed in the brains of HIV-infected patients with HIV-associated neurocognitive disorders (HAND). These disorders characterize a spectrum neurological syndrome that affects up to one-fourth of all HIV/AID-infected humans. Three proposed mechanism contribute to HAND, those given were gene tic host susceptibility factors, viral properties, and altered host immune responses. The first factor listed (altered host expressions)Read MoreEssay On Biogenesis1150 Words   |  5 Pagesin BC compared with CP progenitors. This signaling pathway increases the ADAR1 expression in progenitor LSCs and promotes ADAR1-mediated A-to-I editing. Furthermore, ADAR1 impairs biogenesis of tumour suppressive miRNAs, thereby contributing to cancer progression. Since the let-7 miRNA family is also related to self renewal of LSC, it led the authors to investigate the correlation between JAK2/STAT pathway and LIN28B/let-7-axis, they hypothesized that the LIN28B/let-7self-renewal axis may also beRead MoreEssay On Exosomes988 Words   |  4 Pagesseries of sample, but the striking evidences provided by Melo and colleague suggests that GPC1+ exosomes may serve as a potential diagnostic and screening biomarker to detect early stages of PC for possible curative surgery. In earlier studies, overex pression of survivin380, and mislocalisation of plectin381 in exosomes were also proposed as a biomarkers for PC. Moreover, it has also recently been found that a higher rate of patients with localized PC showed noticeable KRAS mutations in exosomal DNARead MoreSymptoms And Treatment Of Renal Disorders Essay4299 Words   |  18 PagesAbstract MicroRNAs (miRNA) are endogenously produced short non-coding regulatory RNAs that can repress gene expression by posttranscriptional mechanisms. They can therefore influence both normal and pathological conditions in diverse biological systems. Several miRNAs have been detected in kidneys where they have been found to be crucial for renal development and normal physiological functions as well as significant contributors to the pathogenesis of renal disorders such as diabetic nephropathy

Friday, December 13, 2019

Short Story evaluation template Free Essays

A good short story includes the following: Interesting appropriate title plot Theme / message Narrative style: telling a story Structure: Introduction, development, conflict, climax, resolution / conclusion Strong Introduction conclusion: Introduction hooks the reader, conclusion leaves a lasting Impression on the reader. Conflict/ Issue / problem: Introduced resolved. Suspense: The story must hold the reader’s Interest. We will write a custom essay sample on Short Story evaluation template or any similar topic only for you Order Now The problem presented early In the story Is developed steadily so that the reader’s curiously Is stimulated; the reader then becomes more and more Involved In the story. Suspense reaches the highest point at the climax: this is the point where the problem Is resolved In some way. This then leads to the resolutions of the story. Tense: clear and consistent Distinctive tone: formal, informal, chatty, lively, exciting etc.. Strong, interesting and varied characters Narrator: who tells the story? Clear point of view: first / third person Paragraphs Good punctuation, spelling grammar Setting: time place Varied range of expression: adjectives, verbs, similes, metaphors, sensual images language, color, varied sentence length (short long: allows description and creates tension suspense) Dialogue: gives a good insight into characters, life styles, personalities, relationships Proof read: have you answered who, what, when, where, why how questions Resolution: open or closed ending. How to cite Short Story evaluation template, Papers

Thursday, December 5, 2019

Alice Walkers Am I Blue free essay sample

Alice Walkers essay Am I Blue? , is on the surface, a statement about how humans treat animals and the rights of animals. However, on a deeper level, Walker is making a very powerful argument about how human animals treat each other much the same way they treat non human animals. All though history, horses have been symbols of power and grace. Gigantic herds of mustangs were once seen galloping on the American frontier. Alice Walker brings you to her reality, with the story of a beautiful horse named Blue. She uses great imagery, personification and socially thought provoking analogies to build emotional sentiment for her central ideas and effectively persuade you to see her point of view. She incorporates her techniques so well that the reader is left with an entirely new, or at the very least, greatly supported view of a horse’s life and animal captivity. Alice Walkers extraordinary use of imagery effectively creates scenes of beautiful country life in the readers mind. We will write a custom essay sample on Alice Walkers Am I Blue or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page A reader can brilliantly picture a large meadow running strait from a porch into the mountains. Her Descriptions of Blue flipping its mane, added with the scenery of the five acres, develops a full scene that one can truly observe and feel. This technique of imagery not only captures the reader’s attention, but gives the reader a firsthand view from the eyes of the writer. This leads to a greater effect when Alice surfaces arguments from her experience. Alices great use of imagery helps to enhance all aspects of her story. This story of the solitary misery of a neighbor’s horse evokes so much empathy in Alice Walker that she quits eating meat. Am I Blue is about a fond relationship between a horse and a woman. However, one may wonder if there is much more to the story than what the words say. In Am I Blue, Alice Walker conveys her high regard towards animal rights through the use of many different rhetorical devices such as description, anecdote, metaphor, personificat ion, irony, and analogy. After analyzing each technique used by the author, one can clearly say that her purpose for using such literary devices is to argue that there are human qualities in animals. Respectively, she says that through gestures, signs, and expressions, animals are in a sense, linked to humans. The story begins with a brief description about a relationship with a horse that is boarded on the farm next to where Walker lived at the time. The tender relationship began with the ritual of feeding Blue, the magnificent horse. In her story, she traces her relationship with Blue over the numerous years she had spent with him. She describes in vast detail about the life altering events they both had experienced. Walker’s perceptions of Blue are revealed through the use of description. There are people who consider that animals do not have rights and that they actually want to be abused by humans. This was a very hard short story to find. I wanted to know why, so I looked for biographies of Alice Walker. I found that she had two short stories banned. One was Am I Blue? The other was Roselily. The only reasoning I could see for this was some of the language used. In 1982, Walker went on to win a Pulitzer Prize for â€Å"The Color Purple†. Walker is an amazing writer and has a flair with words, although a bit controversial, that allows her readers to immerse themselves into her writings. To conclude, I believe Alice Walker did a fantastic job through her use of imagery, personification and analogy, to place the reader directly in her shoes. Once through reading the story, one cant help but feel sorry for Blue. Alices arguments of fair animal treatment arise as clear and understandable because of her great use of imagery, personification, and analogy. Alice Walker can produce fascinating scenes of beauty and sorrow which any reader can appreciate and enjoy. Alice Walker continues not only to write, but to be active in environmental, feminist/womanist causes, and issues of economic justice.